Biosynthesized tea polyphenols inactivate Chlamydia trachomatis in vitro.
نویسندگان
چکیده
Biosynthesized tea polyphenols showed antichlamydial activity against Chlamydia trachomatis D/UW-3/Cx and L2/434/Bu using cell culture. The most active compounds were (-)-epigallocatechin gallate and (-)-epicatechin gallate, followed by (-)-epicatechin (EC). (+)-Epicatechin and (-)-epigallocatechin were intermediate. EC was the least toxic. These results warrant evaluation of tea polyphenols as topical antichlamydial agents.
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 49 6 شماره
صفحات -
تاریخ انتشار 2005